Synergism happens when an effect, beneficial or otherwise, happens when two drugs are used together. The effects of both drugs are weakened, which may encourage the person to use more despite the fact that there are already high levels in their blood. This can happen when Xanax, a sedative, is taken with a stimulant such as cocaine. Sometimes, the effects of both are reduced.
AntagonismĪntagonism happens when two drugs are taken together and one reduces the effect of the other. Three of these are antagonism, synergism, and metabolic interactions. Xanax and other substances or even bodily systems can interact in other ways. This can easily lead to an overdose as both drugs work to decrease the patient’s breathing, heart rate, and other CNS actions.Ī person who engages in polysubstance abuse with Xanax and chooses to consume grapefruit juice could easily overdose. This can be seen when the person takes Xanax with alcohol or an opioid. The dangers of potentiating alprazolam increase when Xanax is taken with another substance that enhances its effects or enhances the effects of both substances. The real dangers of mixing grapefruit juice and Xanax come when the person tries to operate heavy machinery like a car. This combination may even bring on symptoms that Xanax is supposed to ease, such as anxiety, restlessness, and suicidal ideation. The side effects of mixing grapefruit juice and Xanax include: Side Effects Of Mixing Xanax And Grapefruit Juiceĭue to the way grapefruit juice interferes with the breakdown of Xanax in the body, a person may experience multiple effects when mixing the substances. When this enzyme doesn’t work, the amount of Xanax in the system can build up to dangerous levels.Īs a result, taking grapefruit juice and Xanax together can lead to an overdose even if the person takes what they believe is a normal dose. These chemicals are called furanocoumarins, and they stop the action of an enzyme called CYP3A4. Xanax is one drug that should never be taken with grapefruit juice because the juice contains a chemical that can affect the liver enzymes that metabolize Xanax.
Surprisingly, grapefruit juice is actually capable of causing negative drug interactions. These combinations can increase the risk of serious side effects. This drug has habit-forming qualities, so doctors prescribe it for short-term use only.įorms of Xanax abuse include mixing it with other drugs and even grapefruit juice. Xanax, which is the brand name for alprazolam, is a type of sedative called a benzodiazepine. Treatment for Xanax abuse can help a person avoid these side effects and manage substance abuse and addictive behaviors in order to enter recovery. Mixing grapefruit juice and Xanax (potentiating Xanax) can have harmful to dangerous consequences.
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